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Article

Leveraging gene-environment interactions and endotypes for asthma gene discovery.

The Journal of allergy and clinical immunology - 1 Mar 2016

Bønnelykke Klaus, Ober Carole

Abstract excerpt

Asthma is a heterogeneous clinical syndrome that includes subtypes of disease with different underlying causes and disease mechanisms. Asthma is caused by a complex interaction between genes and environmental exposures; early-life exposures in particular play an important role. Asthma is also heritable, and a number of susceptibility variants have been discovered in genome-wide association studies, although the...

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Identifiers

PMID: 26947980
DOI: 10.1016/j.jaci.2016.01.006
PMCID: PMC5004762

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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