Gene-environment interactions in asthma.

doi:10.1016/j.jaci.2008.10.046

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Article

Gene-environment interactions in asthma.

The Journal of allergy and clinical immunology - 1 Jan 2009

von Mutius Erika

Abstract excerpt

Asthma is a complex disease, and its incidence is determined by an intricate interplay of genetic and environmental factors. The identification of novel genes for asthma suggests that many genes with small effects rather than few genes with strong effects contribute to the development of asthma. These genetic effects may in part differ with respect to a subject's environmental exposures, although some genes may...

Topics

Animals
Asthma
Environmental Exposure
Genetic Variation
Humans

Source

Open in PubMed

Identifiers

PMID: 19130922
DOI: 10.1016/j.jaci.2008.10.046

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