Article
[Correlations of polymorphisms of TGFB1 and TGFBR2 genes to genetic susceptibility to gastric cancer].
Ai zheng = Aizheng = Chinese journal of cancer - 1 Jun 2007
Zhou Yan, Jin Guang-Fu, Jiang Guo-Jun, Wang Hong-Min, Tan Yong-Fei, Ding Wei-Liang, Wang Li-Na, Chen Wen-Sen, Ke Qiao, Shen Jing, Xu Yao-Chu, Shen Hong-Bing
Abstract excerpt
BACKGROUND & OBJECTIVE: Transforming growth factor beta (TGFbeta) signaling pathway plays an important role in the genesis and progression of tumors through regulating cell proliferation and differentiation. The concentration of TGFbeta1 in plasma and the expression of TGFbeta receptor II (TGFbetaRII) are correlated to the development of certain tumors, including gastric cancer. This study was to explore the...
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