Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Intensity of HLA class I expression and KIR‐mismatch determine NK‐cell mediated lysis of leukaemic blasts from children with acute lymphatic leukaemia

6 Jun 2007

Abstract excerpt

The impact of human leucocyte antigen (HLA) class I expression intensity and killer-cell immunoglobulin-like receptor (KIR)-mismatch was investigated on natural killer (NK)-cell mediated lysis of B-lineage leukaemic blasts from 21 paediatric patients in vitro. Blast susceptibility to standardised NK-activity and HLA-expression differed widely. A clear association between HLA-molecules/cell (range 442 000-13 000)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hematopoietic Stem Cell Transplantation
Share to Immune Cell Function and Interaction
Share to T-cell and B-cell Immunology

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 17555452
DOI: 10.1111/j.1365-2141.2007.06631.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Intensity of HLA class I expression and KIR‐mismatch determine NK‐cell mediated lysis of leukaemic blasts from children with acute lymphatic leukaemiaPMID 17555452Read ↗

Cytolytic activity of NK cell clones against acute childhood precursor-B-cell leukaemia is influenced by HLA class I expression on blasts and the differential KIR phenotype of NK clones.Semantic proximity Read ↗

Determinants of Antileukemia Effects of Allogeneic NK CellsSemantic proximity Read ↗

NKG2D Signaling Leads to NK Cell Mediated Lysis of Childhood AML.Semantic proximity Read ↗

Genotypes of NK cell KIR receptors, their ligands, and Fcγ receptors in the response of neuroblastoma patients to Hu14.18-IL2 immunotherapy.Semantic proximity Read ↗

The relevance of natural killer cell human leucocyte antigen epitopes and killer cell immunoglobulin‐like receptors in bone marrow transplantationSemantic proximity Read ↗

Evaluation of KIR ligand incompatibility in mismatched unrelated donor hematopoietic transplants. Killer immunoglobulin-like receptor.Semantic proximity Read ↗

Susceptibility of adult acute lymphoblastic leukemia blasts to lysis by lymphokine-activated killer cells.Semantic proximity Read ↗

Role of the inhibitory KIR ligand HLA-Bw4 and HLA-C expression levels in the recognition of leukemic cells by Natural Killer cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.