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Determinants of Antileukemia Effects of Allogeneic NK Cells

1 Jan 2004

Abstract excerpt

In HLA-nonidentical bone marrow transplantation, we studied the characteristics of donor NK cells, recipient leukemia cells, and the cytokine environment that predict the antileukemia effects of allogeneic NK cells. We found that the risk of relapse in pediatric patients with hematologic malignancies was best predicted by a model taking into consideration the presence of inhibitory killer cell Ig-like receptors...

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PMID: 14688377
DOI: 10.4049/jimmunol.172.1.644

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