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The relevance of natural killer cell human leucocyte antigen epitopes and killer cell immunoglobulin‐like receptors in bone marrow transplantation

7 Nov 2005

Abstract excerpt

The discovery that killer cell immunoglobulin-like receptors (KIR) interact with genetically polymorphic epitopes on class I human leucocyte antigen (HLA) molecules and that the KIR receptor repertoire itself is genetically variable has led to investigation of the relevance of the KIR system to stem cell transplantation. A number of retrospective studies of transplant outcome have now demonstrated either...

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Share to Hematopoietic Stem Cell Transplantation
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PMID: 16359351
DOI: 10.1111/j.1423-0410.2005.00712.x

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