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Article

Genotypes of NK cell KIR receptors, their ligands, and Fcγ receptors in the response of neuroblastoma patients to Hu14.18-IL2 immunotherapy.

Cancer research - 1 Dec 2010

Delgado David C, Hank Jacquelyn A, Kolesar Jill, Lorentzen David, Gan Jacek, Seo Songwon, Kim Kyungmann, Shusterman Suzanne, Gillies Stephen D, Reisfeld Ralph A, Yang Richard, Gadbaw Brian, DeSantes Kenneth B, London Wendy B, Seeger Robert C, Maris John M, Sondel Paul M

Abstract excerpt

Response to immunocytokine (IC) therapy is dependent on natural killer cells in murine neuroblastoma (NBL) models. Furthermore, killer immunoglobulin-like receptor (KIR)/KIR-ligand mismatch is associated with improved outcome to autologous stem cell transplant for NBL. Additionally, clinical antitumor response to monoclonal antibodies has been associated with specific polymorphic-FcγR alleles. Relapsed/refractory...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20935224
DOI: 10.1158/0008-5472.CAN-10-2211
PMCID: PMC2999644

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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