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Article

Variable switching rates of malaria virulence genes are associated with chromosomal position.

Molecular microbiology - 1 Jun 2007

Frank Matthias, Dzikowski Ron, Amulic Borko, Deitsch Kirk

Abstract excerpt

Antigenic variation in Plasmodium falciparum malaria is mediated by transcriptional switches between different members of the multicopy var gene family. Each var gene encodes a member of a group of heterogeneous surface proteins collectively referred to as PfEMP1. Mutually exclusive expression ensures that an individual parasite only transcribes a single var gene at a time. In this work we studied var gene...

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Identifiers

PMID: 17555435
DOI: 10.1111/j.1365-2958.2007.05736.x
PMCID: PMC3634120

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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