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Article

Control of DNA methylation and heterochromatic silencing by histone H2B deubiquitination.

Nature - 7 Jun 2007

Sridhar Vaniyambadi V, Kapoor Avnish, Zhang Kangling, Zhu Jianjun, Zhou Tao, Hasegawa Paul M, Bressan Ray A, Zhu Jian-Kang

Abstract excerpt

Epigenetic regulation involves reversible changes in DNA methylation and/or histone modification patterns. Short interfering RNAs (siRNAs) can direct DNA methylation and heterochromatic histone modifications, causing sequence-specific transcriptional gene silencing. In animals and yeast, histone H2B is known to be monoubiquitinated, and this regulates the methylation of histone H3 (refs 10, 11). However, the...

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PMID: 17554311
DOI: 10.1038/nature05864

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Control of DNA methylation and heterochromatic silencing by histone H2B deubiquitination.PMID 17554311Read ↗

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Histone H2B monoubiquitination regulates salt stress-induced microtubule depolymerization in Arabidopsis.Semantic proximity Read ↗

Microarray Analysis Reveals Potential Biological Functions of Histone H2B Monoubiquitination.Semantic proximity Read ↗

Ubiquitination of histone H2B regulates H3 methylation and gene silencing in yeast.Semantic proximity Read ↗

Histone H2B monoubiquitination facilitates the rapid modulation of gene expression during Arabidopsis photomorphogenesis.Semantic proximity Read ↗

Ubiquitylation of the COMPASS component Swd2 links H2B ubiquitylation to H3K4 trimethylation.Semantic proximity Read ↗

Histone H2BK123 monoubiquitination is the critical determinant for H3K4 and H3K79 trimethylation by COMPASS and Dot1.Semantic proximity Read ↗

Histone H2B monoubiquitination in the chromatin of FLOWERING LOCUS C regulates flowering time in Arabidopsis.Semantic proximity Read ↗

Arabidopsis UEV1D promotes Lysine-63-linked polyubiquitination and is involved in DNA damage response.Semantic proximity Read ↗

Proteasomal ATPases link ubiquitylation of histone H2B to methylation of histone H3.Semantic proximity Read ↗

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