Article
Arabidopsis UEV1D promotes Lysine-63-linked polyubiquitination and is involved in DNA damage response.
The Plant cell - 1 Jan 2008
Wen Rui, Torres-Acosta J Antonio, Pastushok Landon, Lai Xiaoqin, Pelzer Lindsay, Wang Hong, Xiao Wei
Abstract excerpt
DNA damage tolerance (DDT) in budding yeast requires Lys-63-linked polyubiquitination of the proliferating cell nuclear antigen. The ubiquitin-conjugating enzyme Ubc13 and the Ubc enzyme variant (Uev) methyl methanesulfonate2 (Mms2) are required for this process. Mms2 homologs have been found in all eukaryotic genomes examined; however, their roles in multicellular eukaryotes have not been elucidated. We report...
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