Article
Susceptibility of cancer cells to herpes simplex virus-dependent apoptosis.
The Journal of general virology - 1 Jul 2007
Nguyen Marie L, Kraft Rachel M, Blaho John A
Abstract excerpt
Apoptosis has recently been associated with herpes simplex virus 1 (HSV-1) latency and disease severity. There is an intricate balance between pro- and anti-apoptotic processes during HSV-1 infection. When anti-apoptotic pathways are suppressed, this balance is upset and the cells die by apoptosis, referred to here as HSV-1-dependent apoptosis (HDAP). It has been observed previously that HeLa cancer cells exhibit...
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