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Article

Reduced tumorigenicity and pathogenicity of cervical carcinoma SiHa cells selected for resistance to cidofovir.

Molecular cancer - 10 Dec 2013

De Schutter Tim, Andrei Graciela, Topalis Dimitri, Duraffour Sophie, Mitera Tania, van den Oord Joost, Matthys Patrick, Snoeck Robert

Abstract excerpt

BACKGROUND: Insights into the mechanisms associated with chemotherapy-resistance are important for implementation of therapeutic strategies and for unraveling the mode of action of chemotherapeutics. Although cidofovir (CDV) has proven efficacious in the treatment of human papillomavirus (HPV)-induced proliferation, no studies concerning the development of resistance to CDV in HPV-positive tumor cells have been...

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Identifiers

PMID: 24325392
DOI: 10.1186/1476-4598-12-158
PMCID: PMC4029382

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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