Article
Protection by herpes simplex virus glycoprotein D against Fas-mediated apoptosis: role of nuclear factor kappaB.
The Journal of biological chemistry - 19 Sept 2003
Medici M Antonietta, Sciortino M Teresa, Perri Donata, Amici Carla, Avitabile Elisa, Ciotti Marco, Balestrieri Emanuela, De Smaele Enrico, Franzoso Guido, Mastino Antonio
Abstract excerpt
Signals involved in protection against apoptosis by herpes simplex virus 1 (HSV-1) were investigated. Using U937 monocytoid cells as an experimental model, we have demonstrated that HSV-1 rendered these cells resistant to Fas-induced apoptosis promptly after infection. UV-inactivated virus as wel...
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