Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Induction of apoptosis by herpes simplex virus type 1.

1 Nov 1997

Abstract excerpt

Although herpes simplex virus type 1 (HSV-1) does not induce apoptosis in infected HEp-2 cells, in the presence of cycloheximide infection induced apoptosis with characteristic morphological changes as well as endonucleosomal DNA cleavage. The induction of apoptosis without de novo protein synthesis suggests that a structural protein of the HSV-1 virion is responsible for the observed apoptosis. Apoptosis or...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Herpesvirus Infections and Treatments
Share to Viral Infectious Diseases and Gene Expression in Insects
Share to Virus-based gene therapy research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 9367378
DOI: 10.1099/0022-1317-78-11-2909

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Induction of apoptosis by herpes simplex virus type 1.PMID 9367378Read ↗

Herpes simplex virus 1 induces and blocks apoptosis at multiple steps during infection and protects cells from exogenous inducers in a cell-type-dependent mannerSemantic proximity Read ↗

Varicella-zoster virus induces apoptosis in cell cultureSemantic proximity Read ↗

ICP0 Gene Expression Is a Herpes Simplex Virus Type 1 Apoptotic TriggerSemantic proximity Read ↗

Accumulation of herpes simplex virus type 1 early and leaky-late proteins correlates with apoptosis prevention in infected human HEp-2 cells.Semantic proximity Read ↗

Modulation of apoptosis during herpes simplex virus infection in human cellsSemantic proximity Read ↗

The herpes simplex virus major regulatory protein ICP4 blocks apoptosis induced by the virus or by hyperthermia.Semantic proximity Read ↗

Type I interferons are essential mediators of apoptotic death in virally infected cellsSemantic proximity Read ↗

The interplay between human herpes simplex virus infection and the apoptosis and necroptosis cell death pathwaysSemantic proximity Read ↗

The Herpes Simplex Virus Type 1 Regulatory Protein ICP27 Is Required for the Prevention of Apoptosis in Infected Human CellsSemantic proximity Read ↗

Activation of Human Herpesvirus Replication by ApoptosisSemantic proximity Read ↗

Protection by herpes simplex virus glycoprotein D against Fas-mediated apoptosis: role of nuclear factor kappaB.Semantic proximity Read ↗

Herpes simplex virus type 1 immediate-early gene expression is required for the induction of apoptosis in human epithelial HEp-2 cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.