Article
FGF signaling in mandibular skeletogenesis.
Orthodontics & craniofacial research - 1 May 2007
Mina Mina, Havens Bruce, Velonis D A
Abstract excerpt
OBJECTIVE: To examine the functions of FGF/FGFR signaling during mandibular skeletogenesis in ovo. DESIGN: We examined the effects of inhibition of FGF signaling during mandibular skeletogenesis by overexpressing replication-competent RCAS virus encoding a truncated form of FGFR3 in the chicken mandibular process between stages 17 and 26. RESULTS: Injection of RCAS-dnFGFR3 into the developing mandible resulted in...
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