Loss of fibroblast growth factor receptors is necessary for terminal differentiation of embryonic limb muscle.

doi:10.1242/dev.122.1.291

Back to search

Article

Loss of fibroblast growth factor receptors is necessary for terminal differentiation of embryonic limb muscle.

Development (Cambridge, England) - 1 Jan 1996

Itoh N, Mima T, Mikawa T

Abstract excerpt

Early in embryogenesis, precursors of the limb musculature are generated in the somite, migrate to the limb buds and undergo terminal differentiation. Although myogenic differentiation in culture is affected by several growth factors including fibroblast growth factor (FGF), it remains uncertain...

Topics

Animals
Chick Embryo
Extremities
Fibroblast Growth Factors
Gene Expression Regulation, Developmental
Muscle, Skeletal
Mutation
Receptors, Fibroblast Growth Factor
Retroviridae
Signal Transduction
Up-Regulation

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.