Article
Morphogenesis of the medial region of the developing mandible is regulated by multiple signaling pathways.
Cells, tissues, organs - 1 Jan 2001
Mina M
Abstract excerpt
Experimental evidence indicates that the mandibular primordia are specified as at least two independent functional regions: two large lateral (proximal) regions where morphogenesis is dependent on FGF-8 signaling, and a small medial region where morphogenesis is independent of FGF-8 and dependent on other signals. The patterns of expression of multiple signaling molecules and regulatory genes in the epithelium...
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