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Article

Influence of interleukin 10 promoter polymorphisms in susceptibility to giant cell arteritis in Northwestern Spain.

The Journal of rheumatology - 1 Jul 2007

Rueda Blanca, Roibas Begoña, Martin Javier, Gonzalez-Gay Miguel A

Abstract excerpt

OBJECTIVE: Proinflammatory cytokines such as interferon-g (IFN-g) play an important role in the pathogenesis of giant cell arteritis (GCA). Interleukin 10 (IL-10) is a Th2 cytokine with a suppressor effect on IFN-g production. We assessed the influence of functional IL-10 gene promoter polymorphisms in susceptibility to GCA in individuals from Northwestern Spain. METHODS: One hundred three patients with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17552041

Genes

GCA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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