Article
The intimate relationship between gut and joint in spondyloarthropathies.
Current opinion in rheumatology - 1 Jul 2007
Jacques Peggy, Mielants Herman, Coppieters Ken, De Vos Martine, Elewaut Dirk
Abstract excerpt
PURPOSE OF REVIEW: The aim of this article is to highlight recent progress in the combined joint and gut disease in spondyloarthropathies. RECENT FINDINGS: A set of genes has been identified that are differentially expressed in the colon of spondyloarthropathy and Crohn's disease patients. Reduction of human leukocyte antigen B27 (HLA B27) misfolding by additional beta2-microglobulin in HLA B27 transgenic rats...
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