Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The interaction between host genetics and the microbiome in the pathogenesis of spondyloarthropathies.

Current opinion in rheumatology - 1 Jul 2016

Asquith Mark, Rosenbaum James T

Abstract excerpt

PURPOSE OF REVIEW: The intestinal microbiome is increasingly implicated in the pathogenesis of ankylosing spondylitis, reactive arthritis, and other diseases collectively known as the spondyloarthropathies (SpAs). In common with other complex inflammatory diseases, SpAs have both a strong genetic and environmental component. Recent genetic studies have highlighted host pathways that may intersect the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aminopeptidases
Share to Gastrointestinal Microbiome
Share to RUNX3 gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to HLA-B27 Antigen

Share to Minor Histocompatibility Antigens

Share to Spondylarthropathies

Share to Spondylitis, Ankylosing

Source

Identifiers

PMID: 27152700
DOI: 10.1097/BOR.0000000000000299

Genes

ERAP1
ERAP2
RUNX3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The interaction between host genetics and the microbiome in the pathogenesis of spondyloarthropathies.PMID 27152700Read ↗

The role of the gut and intestinal dysbiosis in the pathogenesis of spondyloarthritis.Semantic proximity Read ↗

The role of gut microbiota and IL-23/IL-17 pathway in ankylosing spondylitis immunopathogenesis: New insights and updates.Semantic proximity Read ↗

Gut microbiota-microRNA interactions in ankylosing spondylitis.Semantic proximity Read ↗

Exploring the Pathogenesis of Spondylarthritis beyond HLA-B27: A Descriptive Review.Semantic proximity Read ↗

Putative Pathobionts in HLA-B27-Associated SpondyloarthropathySemantic proximity Read ↗

Gut microbiota in axial spondyloarthritis : genetics, medications and future treatmentsSemantic proximity Read ↗

Both Disease Activity and HLA–B27 Status Are Associated With Gut Microbiome Dysbiosis in Spondyloarthritis PatientsSemantic proximity Read ↗

Arthritis susceptibility and the gut microbiomeSemantic proximity Read ↗

Genetics of Ankylosing Spondylitis—Focusing on the Ethnic Difference Between East Asia and EuropeSemantic proximity Read ↗

The Potential Role of Genetics, Environmental Factors, and Gut Dysbiosis in the Aberrant Non-Coding RNA Expression to Mediate Inflammation and Osteoclastogenic/Osteogenic Differentiation in Ankylosing SpondylitisSemantic proximity Read ↗

Gut Microbiota Perturbations in Reactive Arthritis and Postinfectious SpondyloarthritisSemantic proximity Read ↗

The intestinal microbiome in spondyloarthritisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.