Article
Revisiting the gut-joint axis: links between gut inflammation and spondyloarthritis.
Nature reviews. Rheumatology - 1 Aug 2020
Gracey Eric, Vereecke Lars, McGovern Dermot, Fröhling Mareike, Schett Georg, Danese Silvio, De Vos Martine, Van den Bosch Filip, Elewaut Dirk
Abstract excerpt
Gut inflammation is strongly associated with spondyloarthritis (SpA), as exemplified by the high prevalence of inflammatory bowel disease (IBD) and the even higher occurrence of subclinical gut inflammation in patients with SpA. The gut-joint axis of inflammation in SpA is further reinforced by similarities in immunopathogenesis at both anatomical sites and by the clinical success of therapies blocking TNF and...
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