Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association between germline variation in the FHIT gene and prostate cancer in Caucasians and African Americans.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jun 2007

Levin Albert M, Ray Anna M, Zuhlke Kimberly A, Douglas Julie A, Cooney Kathleen A

Abstract excerpt

Many studies have established that loss of heterozygosity and/or altered expression of the fragile histidine triad (FHIT) gene is a common event in a number of tumor types including prostate carcinoma. Encompassing the most active fragile site in the human genome, FRA3B, FHIT has become the model...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Prostatic Neoplasms
Share to Acid Anhydride Hydrolases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Black or African American

Share to Linkage Disequilibrium

Share to Neoplasm Proteins

Share to Polymorphism, Single Nucleotide

Share to White People

Source

Identifiers

PMID: 17548701
DOI: 10.1158/1055-9965.EPI-06-1054

Genes

FHIT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17548701-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association between germline variation in the FHIT gene and prostate cancer in Caucasians and African Americans.PMID 17548701Read ↗

Strong signature of natural selection within an FHIT intron implicated in prostate cancer risk.Semantic proximity Read ↗

Genetic linkage of prostate cancer risk to the chromosome 3 region bearing FHIT.Semantic proximity Read ↗

Rare Variation in TET2 Is Associated with Clinically Relevant Prostate Carcinoma in African Americans.Semantic proximity Read ↗

FHITness and cancer.Semantic proximity Read ↗

A haplotype at chromosome Xq27.2 confers susceptibility to prostate cancer.Semantic proximity Read ↗

Risk of early-onset prostate cancer in relation to germ line polymorphisms of the vitamin D receptor.Semantic proximity Read ↗

Do FHIT gene alterations play a role in human solid tumors?Semantic proximity Read ↗

The androgen receptor CAG and GGN repeat polymorphisms and prostate cancer susceptibility in African-American men: results from the Flint Men's Health Study.Semantic proximity Read ↗

FRA3B and other common fragile sites: the weakest links.Semantic proximity Read ↗

Identification of a novel germline missense mutation of the androgen receptor in African American men with familial prostate cancer.Semantic proximity Read ↗

Inactivation of the FHIT gene favors bladder cancer development.Semantic proximity Read ↗

Prostate cancer screening in high-risk men: African American Hereditary Prostate Cancer Study Network.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.