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Article

Role of Th22 Cells in the Pathogenesis of Autoimmune Diseases.

Frontiers in immunology - 1 Jan 2021

Jiang Qi, Yang Guocan, Xiao Fan, Xie Jue, Wang Shengjun, Lu Liwei, Cui Dawei

Abstract excerpt

Upon antigenic stimulation, naïve CD4+T cells differentiate into different subsets and secrete various cytokines to exert biological effects. Th22 cells, a newly identified CD4+T cell subset,are distinct from the Th1, Th2 and Th17 subsets. Th22 cells secrete certain cytokines such as IL-22, IL-13 and TNF-α, but not others, such as IL-17, IL-4, or interferon-γ (IFN-γ), and they express chemokine receptors CCR4,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34295334
DOI: 10.3389/fimmu.2021.688066
PMCID: PMC8290841

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