Article
Risk of renal cell carcinoma and polymorphism in phase I xenobiotic metabolizing CYP1A1 and CYP2D6 enzymes.
Urologic oncology - 1 Oct 2013
Ahmad Shiekh Tanveer, Arjumand Wani, Seth Amlesh, Nafees Sana, Rashid Summya, Ali Nemat, Hamiza Oday O, Sultana Sarwat
Abstract excerpt
The progressive increase in sporadic renal cell carcinoma (RCC) observed in industrialized countries supports the opinion that certain carcinogens present in the environment (tobacco smoke, drugs, pollutants, and dietary constituents) may affect the occurrence and progression of this disease in developing countries like India. The polymorphism of the enzymes involved in metabolism of such environmental factors...
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