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Article

IcsA surface presentation in Shigella flexneri requires the periplasmic chaperones DegP, Skp, and SurA.

Journal of bacteriology - 1 Aug 2007

Purdy Georgiana E, Fisher Carolyn R, Payne Shelley M

Abstract excerpt

A Shigella flexneri degP mutant, which was defective for plaque formation in Henle cell monolayers, had a reduced amount of IcsA detectable on the bacterial surface with antibody. However, the mutant secreted IcsA to the outer membrane at wild-type levels. This suggests that IcsA adopts an altered conformation in the outer membrane of the degP mutant with reduced exposure on the cell surface. IcsA is, therefore,...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 17526712
DOI: 10.1128/JB.00483-07
PMCID: PMC1951818

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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IcsA surface presentation in Shigella flexneri requires the periplasmic chaperones DegP, Skp, and SurA.PMID 17526712Read ↗

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