Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

SOCS proteins, cytokine signalling and immune regulation

18 May 2007

Abstract excerpt

In this Review, Akihiko Yoshimura and collegues discuss the most recent advances in our understanding of suppressor of cytokine signalling (SOCS) proteins in the regulation of immunity, their involvement in human diseases and the therapeutic implications of targeting this family of cytokine regulators. Suppressor of cytokine signalling (SOCS) proteins are inhibitors of cytokine signalling pathways. Studies have...

Topics

Join the communities discussing this publication.

Cytokine Signaling Pathways and Interactions
interferon and immune responses
Research on Leishmaniasis Studies

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 17525754
DOI: 10.1038/nri2093

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

SOCS proteins, cytokine signalling and immune regulationPMID 17525754Read ↗

SOCS Proteins in Immunity, Inflammatory Diseases, and Immune-Related CancerSemantic proximity Read ↗

SOCS, Inflammation, and AutoimmunitySemantic proximity Read ↗

SOCS: negative regulators of cytokine signaling for immune toleranceSemantic proximity Read ↗

Suppressors of Cytokine Signaling (SOCS) Proteins and JAK/STAT PathwaysSemantic proximity Read ↗

SOCS: suppressors of cytokine signalling.Semantic proximity Read ↗

SOCS signaling in autoimmune diseases: Molecular mechanisms and therapeutic implicationsSemantic proximity Read ↗

SOCS1: a potent and multifaceted regulator of cytokines and cell‐mediated inflammationSemantic proximity Read ↗

Regulation of TLR signaling and inflammation by SOCS family proteinsSemantic proximity Read ↗

SOCS, inflammation, and cancerSemantic proximity Read ↗

Negative regulation of cytokine signaling and immune responses by SOCS proteins.Semantic proximity Read ↗

Suppressor of cytokine signaling proteins as regulators of innate immune signalingSemantic proximity Read ↗

Cytokine signaling in the brain: Putting a SOCS in it?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.