Article
Suppressor of cytokine signaling proteins as regulators of innate immune signaling
26 Oct 2011
Abstract excerpt
The innate immune system builds up the body's first line of defense against invading pathogenic microorganisms. For effective defense of pathogenic invaders, a structured inflammatory reaction has to be initiated that is strongly dependent on cell-to-cell communication. Inflammation in turn is a potentially autodestructive reaction that is tightly controlled to balance antimicrobial activity and host damage....
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