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Article

Fast and easy colorimetric tests for single mismatch recognition by PNA-DNA duplexes with the diethylthiadicarbocyanine dye and succinyl-beta-cyclodextrin.

Journal of biochemical and biophysical methods - 1 Aug 2007

Tedeschi Tullia, Sforza Stefano, Ye Sheng, Corradini Roberto, Dossena Arnaldo, Komiyama Makoto, Marchelli Rosangela

Abstract excerpt

The 3,3'-diethylthiacarbocyanine (DiSC(2)(5)) dye is able to aggregate on full matched PNA-DNA duplexes by changing its absorption properties, which are manifested by an instantaneous colour shift from blue to purple. However the spontaneous aggregation of the dye also on mismatched duplexes and...

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Identifiers

PMID: 17524491
DOI: 10.1016/j.jbbm.2007.04.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17524491-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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