Article
Genetic screening using the colour change of a PNA-DNA hybrid-binding cyanine dye.
Nucleic acids research - 15 Jan 2002
Wilhelmsson L Marcus, Nordén Bengt, Mukherjee Kaushik, Dulay Maria T, Zare Richard N
Abstract excerpt
As the relationship between human genes and various malfunctions and diseases becomes revealed at an ever-increasing pace, the need arises for the development of rapid genetic screening methods for diagnostic purposes. Genetic diseases show great diversity. Some are caused by a few characteristic localised mutations, while others arise from a large number of variations. Hence, it is unlikely that a single,...
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