Article
Positive selection within the Schizophrenia-associated GABA(A) receptor beta(2) gene.
PloS one - 23 May 2007
Lo Wing-Sze, Xu Zhiwen, Yu Zhiliang, Pun Frank W, Ng Siu-Kin, Chen Jianhuan, Tong Ka-Lok, Zhao Cunyou, Xu Xiaojing, Tsang Shui-Ying, Harano Mutsuo, Stöber Gerald, Nimgaonkar Vishwajit L, Xue Hong
Abstract excerpt
The gamma-aminobutyric acid type-A (GABA(A)) receptor plays a major role in inhibitory neurotransmissions. Intronic SNPs and haplotypes in GABRB2, the gene for GABA(A) receptor beta(2) subunit, are associated with schizophrenia and correlated with the expression of two alternatively spliced beta(...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
