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Article

The effect of CYP2D6 polymorphisms on the response to pain treatment for pediatric sickle cell pain crisis.

The Journal of pediatrics - 1 Jun 2007

Brousseau David C, McCarver D Gail, Drendel Amy L, Divakaran Karthika, Panepinto Julie A

Abstract excerpt

OBJECTIVES: To test the hypothesis that children taking hydroxyurea who fail codeine therapy have an increase in reduced-functioning cytochrome P450 2D6 (CYP2D6) alleles. STUDY DESIGN: Children with sickle cell disease presenting to an emergency department with a pain crisis unresponsive to codei...

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Share to Analgesics, Opioid
Share to Anemia, Sickle Cell
Share to Child, Preschool

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Cytochrome P-450 CYP2D6

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Source

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Identifiers

PMID: 17517247
DOI: 10.1016/j.jpeds.2007.01.049
PMCID: PMC1978168

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17517247-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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