Article
Pharmacogenetic Testing for Analgesic Adverse Effects: Pediatric Case Series.
The Clinical journal of pain - 1 Feb 2016
Manworren Renee C B, Jeffries Lauren, Pantaleao Ashley, Seip Richard, Zempsky William T, Ruaño Gualberto
Abstract excerpt
OBJECTIVES: Genetic variants in pharmacokinetic genes can alter the effectiveness and increase the risks of using analgesics to treat pain. The purpose of this retrospective study is to describe the clinical experiences that led to pharmacogenetic testing of pediatric pain management program patients for alterations in the CYP2D6, CYP2C19, and CYP2C9 genes and correlate the analgesic efficacy and adverse...
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