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Article

Inhibitory effect of valproic acid on cytochrome P450 2C9 activity in epilepsy patients.

Basic & clinical pharmacology & toxicology - 1 Jun 2007

Gunes Arzu, Bilir Erhan, Zengil Hakan, Babaoglu Melih O, Bozkurt Atila, Yasar Umit

Abstract excerpt

Drug interactions constitute a major problem in the treatment of epilepsy because drug combinations are so common. Valproic acid is a widely used anticonvulsant drug with a broad therapeutic spectrum. Case reports suggest interaction between valproic acid and other drugs metabolized mainly by cyt...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17516991
DOI: 10.1111/j.1742-7843.2007.00061.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17516991-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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