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Article

Interchromosomal crossover in human cells is associated with long gene conversion tracts.

Molecular and cellular biology - 1 Aug 2007

Neuwirth Efrem A H, Honma Masamitsu, Grosovsky Andrew J

Abstract excerpt

Crossovers have rarely been observed in specific association with interchromosomal gene conversion in mammalian cells. In this investigation two isogenic human B-lymphoblastoid cell lines, TI-112 and TSCER2, were used to select for I-SceI-induced gene conversions that restored function at the sel...

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Share to Chromosome Segregation
Share to Chromosomes, Human
Share to Crossing Over, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Deoxyribonucleases, Type II Site-Specific

Share to Gene Conversion

Share to Genetic Linkage

Share to Loss of Heterozygosity

Share to Saccharomyces cerevisiae Proteins

Source

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Identifiers

PMID: 17515608
DOI: 10.1128/MCB.01852-06
PMCID: PMC1952082

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17515608-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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