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Article

Polymorphisms of Toll-like receptors 2 and 4 in chronically infected hepatitis C patients from north-east Croatia.

Archives of virology - 1 Jan 2015

Perić Magdalena, Bošnjak Zinka, Šarkanj Bojan, Barbić Jerko, Antolović-Požgain Arlen, Ružman Nataša, Roksandić-Križan Ivana, Vuković Dubravka

Abstract excerpt

Chronic infection with hepatitis C virus (HCV) is caused by an inadequate immune response. Experimental data suggest that the impaired activation of Toll-like receptors (TLRs) 2 and 4 contributes to chronic infection. We assessed the distribution of three single-nucleotide polymorphisms (SNPs) in the TLR2 (Arg753Gln) and TLR4 (Asp299Gly/Thr399Ile) genes in individuals from north-east Croatia and their effect on...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25408375
DOI: 10.1007/s00705-014-2283-0

Genes

TLR4
TLR2

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