Article
MTHFR polymorphisms' influence on outcome and toxicity in acute lymphoblastic leukemia patients.
Leukemia research - 1 Dec 2007
Chiusolo Patrizia, Reddiconto Giovanni, Farina Giuliana, Mannocci Alice, Fiorini Alessia, Palladino Mariangela, La Torre Giuseppe, Fianchi Luana, Sorà Federica, Laurenti Luca, Leone Giuseppe, Sica Simona
Abstract excerpt
Recently the influence of polymorphisms of different genes involved in metabolism of chemoterapic agents have been studied especially in childhood acute lymphoblastic leukemia (ALL). We evaluated the influence of C677T and A1298C methylenetetrahydrofolate reductase (MTHFR) polymorphisms on time t...
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