Article
Mutant quantity and quality in mammalian cells (AL) exposed to cesium-137 gamma radiation: effect of caffeine.
Radiation research - 1 Jun 1995
McGuinness S M, Shibuya M L, Ueno A M, Vannais D B, Waldren C A
Abstract excerpt
We examined the effect of caffeine (1,3,7-trimethylxanthine) on the quantity and quality of mutations in cultured mammalian AL human-hamster hybrid cells exposed to 137Cs gamma radiation. At a dose (1.5 mg/ml for 16 h) that reduced the plating efficiency (PE) by 20%, caffeine was not itself a sig...
Topics
- Animals
- Base Sequence
- CHO Cells
- Caffeine
- Cesium Radioisotopes
- Chromosome Mapping
- Chromosomes, Human, Pair 11
- Cricetinae
- DNA Primers
- Gamma Rays
- Genes, Wilms Tumor
- Genotype
- Humans
- Hybrid Cells
- Lymphocytes
- Molecular Sequence Data
- Mutagenesis
- Phenotype