Chromosomal mutations and chromosome loss measured in a new human-hamster hybrid cell line, ALC: studies with colcemid, ultraviolet irradiation, and 137Cs gamma-rays.

doi:10.1016/s0027-5107(97)00117-6

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Article

Chromosomal mutations and chromosome loss measured in a new human-hamster hybrid cell line, ALC: studies with colcemid, ultraviolet irradiation, and 137Cs gamma-rays.

Mutation research - 6 Oct 1997

Kraemer S M, Waldren C A

Abstract excerpt

Small mutations, megabase deletions, and aneuploidy are involved in carcinogenesis and genetic defects, so it is important to be able to quantify these mutations and understand mechanisms of their creation. We have previously quantified a spectrum of mutations, including megabase deletions, in hu...

Topics

Animals
CHO Cells
Chromosome Deletion
Chromosomes, Human, Pair 11
Cricetinae
Demecolcine
Gamma Rays
Humans
Hybrid Cells
Monosomy
Mutagenicity Tests
Mutagens
Mutation
Ultraviolet Rays

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