Article
Plasma corticosterone, dexamethasone (DEX) suppression and DEX/CRH tests in a rat model of genetic vulnerability to depression.
Psychoneuroendocrinology - 1 Jun 2007
Steimer Thierry, Python Agathe, Schulz Pierre E, Aubry Jean-Michel
Abstract excerpt
The hypothalamo-pituitary-adrenal (HPA) axis is hyperactive in major depressive disorder (MDD), and baseline cortisol levels are usually elevated in MDD patients, with alterations of the circadian hormone secretion pattern. The dexamethasone (DEX) suppression test (DST) has been extensively appli...
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