Article
Cannabidiol (CBD) potentiates physiological and behavioral markers of hypothalamic-pituitary-adrenal (HPA) axis responsivity in female and male mice
2024-10-21
Abstract excerpt
<h4>ABSTRACT</h4> <h4>Rationale</h4> Clinical literature indicates there may be a therapeutic use of cannabidiol (CBD) for stress-related disorders. Preclinical literature remains conflicted regarding the underlying neurobehavioral mechanisms, reporting mixed effects of CBD (increased, decreased, or no effect) on anxiety- and fear-related behaviors. Preclinical data demonstrated that CBD modulates hypothalamus-p...
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Identifiers and source
- Literature Corpus work
- b78cc4fa-75ad-5a2a-a82b-58adc13d1868
- DOI
- 10.1101/2024.10.17.618869
