Article
A polymorphism of matrix Gla protein gene is associated with kidney stones.
The Journal of urology - 1 Jun 2007
Gao Bing, Yasui Takahiro, Itoh Yasunori, Tozawa Keiichi, Hayashi Yutaro, Kohri Kenjiro
Abstract excerpt
PURPOSE: Matrix Gla protein, a potent calcification inhibitor in arterial vessels, is also expressed in the kidney and is up-regulated following the administration of ethylene glycol, a precursor of oxalate. Considering the analogous characteristics between arterial calcification and kidney stones, we identified variants of the human matrix Gla protein gene and investigated whether there is an association between...
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