Article
The local calcification inhibitor matrix Gla protein in pseudoxanthoma elasticum.
Clinical biochemistry - 1 Apr 2008
Hendig Doris, Zarbock Ralf, Szliska Christiane, Kleesiek Knut, Götting Christian
Abstract excerpt
OBJECTIVES: Recent studies have revealed the involvement of calcification inhibitory proteins in the pathogenesis of pseudoxanthoma elasticum (PXE). DESIGN AND METHODS: We analyzed serum concentrations of the calcification inhibitor matrix Gla protein (MGP) in a large cohort of patients suffering from PXE (n=101), 34 first-degree relatives and 67 healthy controls. Moreover, we determined the distribution of the...
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