Article
The 434(G>C) polymorphism within the coding sequence of Eosinophil Cationic Protein (ECP) correlates with the natural course of Schistosoma mansoni infection.
International journal for parasitology - 1 Oct 2007
Eriksson Jenny, Reimert Claus M, Kabatereine Narcis B, Kazibwe Francis, Ireri Edmund, Kadzo Hilda, Eltahir Hanan B, Mohamed Abdelrahim O, Vennervald Birgitte J, Venge Per
Abstract excerpt
Schistosomiasis is a chronic parasitic infection with over 200 million people infected worldwide. In Schistosoma mansoni infections, parasite-derived eggs get trapped in the liver, causing the formation of granulomas, which may develop into periportal fibrosis and portal hypertension, and thus severe morbidity. Eosinophil cationic protein (ECP) is a secretory protein of eosinophil granulocytes that efficiently...
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