Article
A pilot study on cytotoxic T lymphocyte-4 gene polymorphisms in urinary schistosomiasis.
Genetic testing and molecular biomarkers - 1 Jun 2012
Idris Zulkarnain Md, Yazdanbakhsh Maria, Adegnika Ayola Akim, Lell Bertrand, Issifou Saadou, Noordin Rahmah
Abstract excerpt
Urinary schistosomiasis is caused by the digenetic trematode Schistosoma haematobium, characterized by accumulation of eggs in the genitourinary tract. Cytotoxic T-lymphocyte antigen 4 (CTLA-4) can play an important role in parasitic infection due to its major role as a negative regulator of T-cell activation and proliferation. This study was performed in patients with schistosomiasis and healthy controls to...
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