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Article

Evolutionary epidemiology of schistosomiasis: linking parasite genetics with disease phenotype in humans.

International journal for parasitology - 1 Feb 2018

Huyse Tine, Boon Nele A M, Van den Broeck Frederik, Mbow Moustapha, Chaturvedi Anurag, Meurs Lynn, Volckaert Filip A M, Polman Katja

Abstract excerpt

Here we assess the role of parasite genetic variation in host disease phenotype in human schistosomiasis by implementing concepts and techniques from environmental association analysis in evolutionary epidemiology. Schistosomiasis is a tropical disease that affects more than 200 million people worldwide and is caused by parasitic flatworms belonging to the genus Schistosoma. While the role of host genetics has...

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PMID: 29154994
DOI: 10.1016/j.ijpara.2017.07.010

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