Article
Polymorphism of the eosinophil cationic protein-gene is related to the expression of allergic symptoms.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 Jul 2002
Jönsson U-B, Byström J, Stålenheim G, Venge P
Abstract excerpt
BACKGROUND: We have found a polymorphism in the ECP (eosinophil cationic protein)-gene at position 434 according to GenBank accession number NM 002935. This polymorphism would cause the change of the amino acid arginine (base at position 434 is G) at position 97 to threonine (base at position 434 is C). OBJECTIVE: To investigate the prevalence of the ECP-polymorphism and to screen for disease associations....
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