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Host genetic background influences the severity of disease in Schistosoma haematobium infections.

Parasite (Paris, France) - 1 Jan 2026

Savassi Boris Sègnito A E, Mahaman Samoussou-Dine K, Biaou Djèlili, Luviano Aparicio Nélia, Ibikounlé Moudachirou, Toulza Eve, Courtin David, Hounkanrin Geoffroy, Massougbodji Achille, Boissier Jérôme

Abstract excerpt

Host genetic factors influence the severity of infectious diseases, including schistosomiasis, which are major public-health burdens in Africa. While the role of host genetic background in Schistosoma mansoni infection has been clearly established, this link remains poorly explored for S. haematobium infections (Sh). Therefore, this study aims to investigate the relationship between genetic background and...

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Genetic Predisposition to Disease
Parasite Egg Count
Polymorphism, Genetic
Promoter Regions, Genetic
Severity of Illness Index

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Tumor Necrosis Factor-alpha

Ultrasonography

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Identifiers

PMID: 41874178
DOI: 10.1051/parasite/2026013
PMCID: PMC13011822

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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