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Article

Polymorphism associated with the Schistosoma mansoni tetraspanin-2 gene.

International journal for parasitology - 1 Oct 2011

Cupit Pauline M, Steinauer Michelle L, Tonnessen Bradley W, Eric Agola L, Kinuthia Joseph M, Mwangi Ibrahim N, Mutuku Martin W, Mkoji Gerald M, Loker Eric S, Cunningham Charles

Abstract excerpt

A vaccine against schistosomiasis would contribute significantly to reducing the 3-70 million disability-adjusted life years lost annually to the disease. Towards this end, inoculation with the large extracellular loop (EC-2) of Schistosoma mansoni tetraspanin-2 protein (Sm-TSP-2) has proved effective in reducing worm and egg burdens in S. mansoni-infected mice. The EC-2 loop of Schistosoma japonicum TSP-2,...

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Identifiers

PMID: 21889508
DOI: 10.1016/j.ijpara.2011.07.007
PMCID: PMC3188324

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Source receipt: pubmed, retrieved 7 Sept 2026.

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