Article
Genetic evidence for a link between glycolysis and DNA replication.
PloS one - 16 May 2007
Jannière Laurent, Canceill Danielle, Suski Catherine, Kanga Sophie, Dalmais Bérengère, Lestini Roxane, Monnier Anne-Françoise, Chapuis Jérôme, Bolotin Alexander, Titok Marina, Le Chatelier Emmanuelle, Ehrlich S Dusko
Abstract excerpt
BACKGROUND: A challenging goal in biology is to understand how the principal cellular functions are integrated so that cells achieve viability and optimal fitness in a wide range of nutritional conditions. METHODOLOGY/PRINCIPAL FINDINGS: We report here a tight link between glycolysis and DNA synthesis. The link, discovered during an analysis of suppressors of thermosensitive replication mutants in bacterium...
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