Article

Oxidative pathways of deoxyribose and deoxyribonate catabolism

2017-10-18

Abstract excerpt

Using genome-wide mutant fitness assays in diverse bacteria, we identified novel oxidative pathways for the catabolism of 2-deoxy-D-ribose and 2-deoxy-D-ribonate. We propose that deoxyribose is oxidized to deoxyribonate, oxidized to ketodeoxyribonate, and cleaved to acetyl-CoA and glyceryl-CoA. We have genetic evidence for this pathway in three genera of bacteria, and we confirmed the oxidation of deoxyribose to k...

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Literature Corpus work: 8d4b8425-a5b3-5991-8094-622d89e130eb
DOI: 10.1101/205583

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